abstract：IMPORTANCE:Cryolipolysis is the noninvasive reduction of fat with localized cutaneous cooling. Since initial introduction, over 650,000 cryolipolysis treatment cycles have been performed worldwide. We present a previously unreported, rare adverse effect following cryolipolysis: paradoxical adipose hyperplasia. OBSERVA...

journal_title：JAMA dermatology

authors： Jalian HR,Avram MM,Garibyan L,Mihm MC,Anderson RR

更新日期：2014-03-01 00:00:00

abstract：IMPORTANCE:Omalizumab has emerged as a novel and effective treatment option for patients with antihistamine-resistant chronic urticaria. It is unclear whether patients with recurrent urticaria symptoms after discontinuation of omalizumab treatment can benefit from retreatment. OBJECTIVE:To assess the response of patie...

journal_title：JAMA dermatology

authors： Metz M,Ohanyan T,Church MK,Maurer M

更新日期：2014-03-01 00:00:00

abstract：IMPORTANCE:Ustekinumab is a human monoclonal antibody that binds to the shared p40 subunit of interleukin (IL) 12 and IL-23. It is approved in the United States for adults (>18 years) with moderate to severe plaque psoriasis who are candidates for phototherapy or systemic therapy. In 1 phase 2 trial of ustekinumab for ...

journal_title：JAMA dermatology

authors： Stamell EF,Kutner A,Viola K,Cohen SR

更新日期：2013-12-01 00:00:00

abstract：IMPORTANCE:Lichen sclerosus (LS) is an uncommon chronic inflammatory disease that most commonly affects anogenital skin of postmenopausal women. It typically manifests as atrophic white plaques, which may be accompanied by purpura or fissuring. Rarely, LS has been observed to affect mucosal tissues in the mouth and the...

journal_title：JAMA dermatology

authors： Zendell K,Edwards L

更新日期：2013-10-01 00:00:00

abstract：IMPORTANCE:Sarcoidosis is a chronic granulomatous disease for which there are limited therapeutic options. This is the first randomized, placebo-controlled study to demonstrate that antimycobacterial therapy reduces lesion diameter and disease severity among patients with chronic cutaneous sarcoidosis. OBJECTIVE:To ev...

journal_title：JAMA dermatology

authors： Drake WP,Oswald-Richter K,Richmond BW,Isom J,Burke VE,Algood H,Braun N,Taylor T,Pandit KV,Aboud C,Yu C,Kaminski N,Boyd AS,King LE

更新日期：2013-09-01 00:00:00

abstract：IMPORTANCE:Hydroxychloroquine-induced pigmentation is not a rare adverse effect. Our data support the hypothesis that hydroxychloroquine-induced pigmentation is secondary to ecchymosis or bruising. OBJECTIVE:To describe the clinical features and outcome of hydroxychloroquine (HCQ)-induced pigmentation in patients with...

journal_title：JAMA dermatology

authors： Jallouli M,Francès C,Piette JC,Huong du LT,Moguelet P,Factor C,Zahr N,Miyara M,Saadoun D,Mathian A,Haroche J,De Gennes C,Leroux G,Chapelon C,Wechsler B,Cacoub P,Amoura Z,Costedoat-Chalumeau N,Plaquenil LUpus Systemic

更新日期：2013-08-01 00:00:00

abstract：IMPORTANCE:Worse survival among patients with melanoma has been demonstrated in middle-aged and older men compared with women, but few studies have explored survival differences by sex in adolescents and young adults, in whom melanoma is the third most common cancer. Focusing on sex disparities in survival among younge...

journal_title：JAMA dermatology

authors： Gamba CS,Clarke CA,Keegan TH,Tao L,Swetter SM

更新日期：2013-08-01 00:00:00

abstract：IMPORTANCE:Recently, a group of melanocytic tumors with loss of BAP1 expression has been described. The lesions may occur sporadically or as part of a familial cancer syndrome. They have distinct histopathologic features characterized by a nevus like silhouette and cytologic composition of large epithelioid melanocytes...

journal_title：JAMA dermatology

authors： Busam KJ,Wanna M,Wiesner T

更新日期：2013-03-01 00:00:00

abstract：IMPORTANCE:Approximately 10% to 25% of patients treated with BRAF inhibitors develop cutaneous squamous cell carcinoma (SCC), but the mechanism responsible has not yet been determined. We report what we believe to be the first case in which Merkel cell polyomavirus (MCPyV) and human papillomavirus subtype 17 (HPV-17) w...

journal_title：JAMA dermatology

authors： Falchook GS,Rady P,Hymes S,Nguyen HP,Tyring SK,Prieto VG,Hong DS,Kurzrock R

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:To compare the prevalence and incidence of type 2 diabetes mellitus between patients with psoriasis and those without psoriasis. DATA SOURCES:MEDLINE, EMBASE, and Cochrane Database of Systematic Reviews between January 1, 1980, and January 1, 2012. STUDY SELECTION:Observational (cohort, case-control, and cr...

journal_title：JAMA dermatology

authors： Armstrong AW,Harskamp CT,Armstrong EJ

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Immune reconstitution inflammatory syndrome (IRIS) is a phenomenon initially described in patients with human immunodeficiency virus. Upon initiation of combination antiretroviral therapy, recovery of cellular immunity triggers inflammation to a preexisting infection or antigen that causes paradoxical worsen...

journal_title：JAMA dermatology

authors： Scharschmidt TC,Amerson EH,Rosenberg OS,Jacobs RA,McCalmont TH,Shinkai K

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVES:To calculate sunbed use prevalence rates, to investigate the motivations for tanning, and to identify typical target groups for interventions to prevent skin cancer. DESIGN:Cross-sectional, representative, population-based study, primary analysis of the SUN-Study 2012 (Sunbed-Use: Needs for Action-Study). ...

journal_title：JAMA dermatology

authors： Schneider S,Diehl K,Bock C,Schlüter M,Breitbart EW,Volkmer B,Greinert R

更新日期：2013-01-01 00:00:00